Pope Leo XIV has been diagnosed with lung adenocarcinoma. According to the Vatican, the tumor was confirmed in tests conducted after the removal of the lower lobe of his right lung. Information about the cancer’s stage and whether it has spread to other organs is not yet available.
What is lung adenocarcinoma?
Lung adenocarcinoma is a type of cancer that develops in glandular cells that produce substances such as mucus. It usually develops in cells lining the airways and lung alveoli, often in the outer parts of the lungs.
It is a type of non-small cell lung cancer (NSCLC), which accounts for about 80-85 percent of lung cancer cases. According to the American Lung Cancer Foundation, adenocarcinoma is the most common subtype, accounting for about 40 percent of all lung cancer cases.
The disease may develop more slowly than some other types of lung cancer, sometimes allowing it to be detected before it spreads. However, its rate of progression varies from patient to patient, and even slow-growing tumors can be dangerous.
Risk factors and symptoms
Smoking is the main risk factor for lung cancer, including adenocarcinoma. However, the disease also affects people who have never smoked and is the most common type of lung cancer in this group. Secondhand smoke, radon, air pollution and exposure to certain hazardous substances at work can also increase the risk. A family history of lung cancer is another risk factor.
Lung adenocarcinoma can develop without obvious symptoms, particularly in its early stages. In some cases, it is found incidentally during medical imaging or a routine examination.
When symptoms occur, they may include a persistent or worsening cough, shortness of breath and wheezing, coughing up blood, chest, shoulder or back pain, unexplained weight loss and prolonged fatigue. These symptoms are not specific to lung cancer and can also have other causes.
The Vatican said the tumor was found during a routine health examination. The Pope described the growth as “well-defined” and said it had been detected at an early stage. Further medical information is needed to determine how advanced the disease is.
Treatment and chances of recovery
Treatment depends on the tumor’s size and location, whether it has spread to nearby lymph nodes or other organs, and the patient’s overall health. When cancer is confined to the lung, surgically removing the tumor may offer the best chance of recovery.
Leo XIV underwent a lobectomy, a procedure in which one of the lung’s lobes is removed. The right lung has three lobes, while the left has two. Surgeons used a video-assisted technique to remove the lower lobe of the Pope’s right lung.
The Vatican said the operation was completed successfully and no complications were reported. It is not yet known whether further treatment will be needed after the procedure to remove the cancerous tissue.
Depending on the cancer’s stage and characteristics, treatment may also include chemotherapy, radiotherapy, targeted therapy or immunotherapy. Targeted therapy acts on specific molecular changes in cancer cells, while immunotherapy helps the immune system fight cancer. Additional treatment may be recommended after surgery if tests indicate that cancer cells may remain or the disease could return.
The prognosis for recovery depends primarily on how far the cancer has spread when it is diagnosed. Doctors determine the stage by considering the tumor’s size and location, whether lymph nodes are affected and whether the cancer has reached other organs.
According to the American Cancer Society, the five-year relative survival rate for non-small cell lung cancer is about 67 percent when the disease is confined to the lung, 40 percent when it has spread to nearby tissue or lymph nodes, and 12 percent when it has spread to distant parts of the body.
These figures reflect outcomes among large groups of patients and do not predict an individual patient’s chances of survival. They apply to all types of non-small cell lung cancer, not just adenocarcinoma. Outcomes can vary depending on the tumor’s characteristics, the patient’s overall health and the treatments available.
What is known about Leo XIV’s condition
The 71-year-old Pope underwent surgery at Rome’s Gemelli Hospital after a growth was detected during a routine health examination. According to the Vatican, tests on tissue removed during the operation confirmed the suspected diagnosis of lung adenocarcinoma.
After the operation, Leo XIV regained consciousness and was taken to a hospital room to recover. The Vatican said he was expected to remain in hospital for about a week and that his public engagements had been canceled through October 20.
Although the diagnosis and successful completion of the operation have been confirmed, the cancer’s stage, whether it has spread and whether the Pope will need additional treatment remain unknown.